| Item type |
Thesis or Dissertation(1) |
| 公開日 |
2022-11-10 |
| タイトル |
|
|
タイトル |
Cytological Kinetics of Periodontal Ligament in an Experimental Occlusal Trauma Model |
|
言語 |
en |
| その他(別言語等)のタイトル |
|
|
その他のタイトル |
実験的咬合性外傷による歯根膜の細胞動態 |
| 作成者(その他言語) |
Takaya, Tatsuo
Hiroaki, Mimura
Matsuda, Saeka
Nakano, Keisuke
Tsujigiwa, Hidetsugu
Tomida, Mihoko
Okafuji, Norimasa
Fujii, Takeo
Kawakami, Toshiyuki
髙谷, 達夫
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Occlusal trauma |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Periodontal tissue |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Green fluorescent protein(GFP) |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Ki67 |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Mouse |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_db06 |
|
資源タイプ |
doctoral thesis |
| アクセス権 |
|
|
アクセス権 |
metadata only access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Using a model of experimental occlusal trauma in mice, we investigated cytological kinetics of periodontal ligament by means of histopathological, immunohistochemical, and photographical analysis methods. At furcation areas of molar teeth in the experimental group on day 4, the increase of cells in periodontal ligament was seen. The cells with a round-shaped nucleus were deeply stained in the hematoxylin-eosin. Ki67 positive nuclei showed a prominent increase in the experimental groups on days 4 and 7. Green Fluorescent Protein (GFP) positivity also revealed cell movement, but this action was slightly slow compared to Ki67 staining specimens. It was indicated that the homeostasis is mechanism of periodontal ligament receiving the excessive occlusal loading was promoted by osteoclasts and macrophages from bone-marrow-derived cells migrated to the periodontal ligament. The remodeling of periodontal ligament with the acceleration of cell growth was evoked from the experiment for the group on day 4 and after day 7. The findings suggested that periodontal ligament at furcation areas of molar teeth in occlusal trauma model was recovered by using both of the cells in situ and the bone-marrow-derived cells. |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
2015 |
| 日付 |
|
|
日付 |
2016-06-02 |
|
日付タイプ |
Created |
| フォーマット |
|
|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| その他の資源識別子 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
甲第174号 |
| 資源識別子URI |
|
|
識別子 |
http://id.nii.ac.jp/1070/00002495/ |
|
識別子タイプ |
URI |
| 情報源 |
|
|
|
関連名称 |
http://www.medsci.org/v12p0544.htm |
| 情報源 |
|
|
|
関連名称 |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502058/ |
| 他の資源との関係 |
|
|
|
関連名称 |
投稿雑誌：Takaya, T. et al. Cytological Kinetics of Periodontal Ligament in an Experimental Occlusal Trauma Model. International Journal of Medical Sciences. 2015; 12(7): 544-551. © 2015 Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 学位授与番号 |
|
|
学位授与番号 |
甲第174号 |
| 学位授与年月日 |
|
|
学位授与年月日 |
2016-02-05 |
| 学位名 |
|
|
学位名 |
博士（歯学） |
| 学位授与機関 |
|
|
|
学位授与機関名 |
松本歯科大学 |
