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Possible association of CUX1 gene polymorphisms with antidepressant response in major depressive disorder
https://shinshu.repo.nii.ac.jp/records/27036
https://shinshu.repo.nii.ac.jp/records/27036db259fac-42ee-4f5f-8d7b-9a4d6bd20eba
名前 / ファイル | ライセンス | アクション |
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https://soar-ir.repo.nii.ac.jp/?action=repository_action_common_download&item_id=3690&item_no=1&attribute_id=65&file_no=1
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Item type | Journal Article(1) | |||||
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公開日 | 2020-09-01 | |||||
タイトル | ||||||
タイトル | Possible association of CUX1 gene polymorphisms with antidepressant response in major depressive disorder | |||||
作成者(その他言語) |
Sasayama, D
× Sasayama, D× Hiraishi, A× Tatsumi, M× Kamijima, K× Ikeda, M× Umene-Nakano, W× Yoshimura, R× Nakamura, J× Iwata, N× Kunugi, H |
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公開者(その他言語) | ||||||
姓名 | NATURE, PUBLISHING GROUP | |||||
書誌情報 |
PHARMACOGENOMICS JOURNAL 巻 13, 号 4, p. 354-358, 発行日 2013-08 |
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言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | antidepressant | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CUX1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | genome-wide association study | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | major depressive disorder | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Association between response to antidepressant treatment and genetic polymorphisms was examined in two independent Japanese samples of patients with major depressive disorder (MDD). Genome-wide approach using the Illumina Human CNV370-quad Bead Chip was utilized in the analysis of the 92 MDD patients in the first sample. In all, 11 non-intergenic single-nucleotide polymorphisms with uncorrected allelic P-value <0.0001 were selected for the subsequent association analyses in the second sample of 136 MDD patients. Difference in allele distribution between responders and nonresponders were found in the second-stage sample for rs365836 and rs201522 of the CUX1 gene (P=0.005 and 0.004, respectively). The allelic P-values for rs365836 and rs201522 in both samples combined were 0.0000023 and 0.0000040, respectively. Our results provide the first evidence that polymorphisms of the CUX1 gene may be associated with response to antidepressant treatment in Japanese patients with MDD. | |||||
日付 | ||||||
日付 | 2015-09-24 | |||||
日付タイプ | Created | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
その他の資源識別子 | ||||||
内容記述タイプ | Other | |||||
内容記述 | PHARMACOGENOMICS JOURNAL. 13(4):354-358 (2013) | |||||
資源識別子URI | ||||||
識別子 | http://hdl.handle.net/10091/17725 | |||||
識別子タイプ | HDL | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1470-269x | |||||
処理レコードID(総合目録DB) | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11703518 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=22584459 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | http://dx.doi.org/10.1038/tpj.2012.18 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |