{"created":"2023-05-15T16:13:25.067534+00:00","id":43949,"links":{},"metadata":{"_buckets":{"deposit":"2abb7897-5609-421b-9d89-e28dcf36e576"},"_deposit":{"created_by":25,"id":"43949","owners":[25],"pid":{"revision_id":0,"type":"depid","value":"43949"},"status":"published"},"_oai":{"id":"oai:shinshu.repo.nii.ac.jp:00043949","sets":[]},"author_link":["171124","171120","171123","171121","171122","171118","171119"],"item_20002_alternative_title_1":{"attribute_name":"その他(別言語等)のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"骨形成蛋白(BMP)誘発異所性骨形成において表示されたtranschondroid bone formation"}]},"item_20002_biblio_info_27":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"26","bibliographicPageStart":"21","bibliographicVolumeNumber":"7","bibliographic_titles":[{"bibliographic_title":"Journal of Hard Tissue Biology"}]}]},"item_20002_creator_3":{"attribute_name":"作成者(その他言語)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kawakami, Toshiyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawai, Tatsushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kimura, Akihiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hasegawa, Hiromasa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshikawa, Yasushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Eda, Shigeo"}],"nameIdentifiers":[{}]}]},"item_20002_date_19":{"attribute_name":"日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-02-12","subitem_date_issued_type":"Created"}]},"item_20002_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"It has been stated that BMP induces undifferentiated mesenchymal cells to become chondrocytes in the first stage of the BMP-induced heterotopic osteogenesis. The cartilage is replaced by bone in a manner similar to that in normal endochondral (indirect) ossification. It is suggested that the BMP induced-bone occurs through an endochondral-like ossification; however the cell differentiation patterns differ from those of the normal fetal endochondral ossification process. On the other hand, intramembranous (direct) ossification is observed in some cases. Therefore, we examined histopathologically the nature of the BMP induced heterotopic osteogenesis, that is, examining histological features that are more like bone than cartilage but whose cells were not distinguishable from chondrocytes. Round chondrocytes-like cells and smaller osteocytelike cells coexisted in the chondroid bone matrix. Furthermore, there were some chondroid patterns that still remained in the maturing bone matrix showing mosaic patterns. These findings seems to be a third ossification pattern, \"transchondroid bone formation\" , which was described by Yasui et al. (1997)11) in an experimentally distraction osteogenesis model in the rat. \"Chondroid bone\", a tissue intermediate between bone and cartilage, was formed mainly in BMP-inducedheterotopic osteogenesis.","subitem_description_type":"Other"}]},"item_20002_description_21":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_20002_full_name_16":{"attribute_name":"公開者(その他言語)","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"Society, for Hard Tissue Regenerative Biology (硬組織再生生物学会)"}]}]},"item_20002_identifier_23":{"attribute_name":"資源識別子URI","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"http://id.nii.ac.jp/1070/00002784/"}]},"item_20002_relation_28":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"雑誌掲載論文(冊子版)"}]}]},"item_20002_relation_60":{"attribute_name":"医中誌ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://search.jamas.or.jp/link/ui/1999024718","subitem_relation_type_select":"ICHUSHI"}}]},"item_20002_rights_50":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 1998 by The Hard Tissue Biology Network Association(JHTBNet)"}]},"item_20002_source_id_25":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-7649","subitem_source_identifier_type":"ISSN"}]},"item_20002_source_id_26":{"attribute_name":"処理レコードID(総合目録DB)","attribute_value_mlt":[{"subitem_source_identifier":"AA11074332","subitem_source_identifier_type":"NCID"}]},"item_20002_version_type_51":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://mdu.repo.nii.ac.jp/?action=repository_action_common_download&item_id=2794&item_no=1&attribute_id=22&file_no=1"}}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"異骨症","subitem_subject_scheme":"Other"},{"subitem_subject":"骨形成因子","subitem_subject_scheme":"Other"},{"subitem_subject":"マウス","subitem_subject_scheme":"Other"},{"subitem_subject":"動物","subitem_subject_scheme":"Other"},{"subitem_subject":"transchondroid bone formation","subitem_subject_scheme":"Other"},{"subitem_subject":"endochondral ossification","subitem_subject_scheme":"Other"},{"subitem_subject":"intramembranous ossification","subitem_subject_scheme":"Other"},{"subitem_subject":"bone morphogenetic protein (BMP)","subitem_subject_scheme":"Other"},{"subitem_subject":"heterotopic osteogenesis","subitem_subject_scheme":"Other"},{"subitem_subject":"chondroid bone","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Transchondroid Bone Formation Displayed in BMP-Induced Heterotopic Osteogenesis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Transchondroid Bone Formation Displayed in BMP-Induced Heterotopic Osteogenesis","subitem_title_language":"en"}]},"item_type_id":"20002","owner":"25","path":["2517","2519","2527"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-04-01"},"publish_date":"2021-04-01","publish_status":"0","recid":"43949","relation_version_is_last":true,"title":["Transchondroid Bone Formation Displayed in BMP-Induced Heterotopic Osteogenesis"],"weko_creator_id":"25","weko_shared_id":-1},"updated":"2023-05-15T17:52:15.003123+00:00"}