{"created":"2023-05-15T15:57:45.594019+00:00","id":27041,"links":{},"metadata":{"_buckets":{"deposit":"fdf96e86-b16c-42a6-8384-9efb9cf45fda"},"_deposit":{"created_by":3,"id":"27041","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"27041"},"status":"published"},"_oai":{"id":"oai:shinshu.repo.nii.ac.jp:00027041","sets":["2668"]},"author_link":["104928","104932","104924","104927","104930","104931","104921","104923","104922","104929","104933","104925","104926"],"item_20002_biblio_info_27":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"1052","bibliographicPageStart":"1047","bibliographicVolumeNumber":"136","bibliographic_titles":[{"bibliographic_title":"JOURNAL OF AFFECTIVE DISORDERS"}]}]},"item_20002_creator_3":{"attribute_name":"作成者(その他言語)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sasayama, Daimei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hori, Hiroaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Teraishi, Toshiya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hattori, Kotaro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ota, Miho"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuo, Junko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawamoto, Yumiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kinoshita, Yukiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hashikura, Miyako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Amano, Naoji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Higuchi, Teruhiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kunugi, Hiroshi"}],"nameIdentifiers":[{}]}]},"item_20002_date_19":{"attribute_name":"日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2015-09-24","subitem_date_issued_type":"Created"}]},"item_20002_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Background: Mood disorders are associated with various neurocognitive deficits. However, few studies have reported the impairment of motor dexterity in unipolar depression and bipolar disorder. In the present study, manual dexterity was compared between unipolar major depression, bipolar disorder, and healthy controls. Methods: Manual dexterity was assessed by the Purdue pegboard test in 98 patients with unipolar major depression, 48 euthymic or depressed patients with bipolar disorder, and 158 healthy controls, matched for age and gender. Results: Compared to healthy controls, sum of the scores of right, left, and both hands subtests (R + L+ B) was significantly lower in both patients with unipolar depression and bipolar disorder (P= 0.0034 and P<0.0001, respectively). Furthermore, R + L + B was significantly lower in bipolar disorder compared to unipolar depression (P=0.0016). Lithium dose and chlorpromazine equivalent dose of antipsychotics were significantly negatively correlated with some of the subtest scores. On the other hand, depression severity did not significantly correlate with any of the subtest scores. Difference in R + L+ B between unipolar depression and bipolar disorder remained statistically significant even after controlling for gender, age, lithium dose, and chlorpromazine equivalent dose (P = 0.0028). Limitations Bipolar patients during manic episode were not included in the study. Conclusions: Gross movement dexterity was impaired in both patients with unipolar depression and bipolar disorder. The severity of impairment was significantly greater in patients with bipolar disorder. The functional difference between unipolar and bipolar patients may suggest different pathological conditions between the two depressive disorders.","subitem_description_type":"Other"}]},"item_20002_description_20":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_20002_description_22":{"attribute_name":"その他の資源識別子","attribute_value_mlt":[{"subitem_description":"JOURNAL OF AFFECTIVE DISORDERS. 136(3):1047-1052 (2012)","subitem_description_type":"Other"}]},"item_20002_full_name_16":{"attribute_name":"公開者(その他言語)","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"ELSEVIER, SCIENCE BV"}]}]},"item_20002_identifier_23":{"attribute_name":"資源識別子URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/10091/17720"}]},"item_20002_relation_31":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=22169250","subitem_relation_type_select":"PMID"}}]},"item_20002_relation_32":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://dx.doi.org/10.1016/j.jad.2011.11.031","subitem_relation_type_select":"DOI"}}]},"item_20002_rights_50":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright© 2011 Elsevier"}]},"item_20002_source_id_25":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0165-0327","subitem_source_identifier_type":"ISSN"}]},"item_20002_source_id_26":{"attribute_name":"処理レコードID(総合目録DB)","attribute_value_mlt":[{"subitem_source_identifier":"AA00256633","subitem_source_identifier_type":"NCID"}]},"item_20002_version_type_51":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://soar-ir.repo.nii.ac.jp/?action=repository_action_common_download&item_id=3695&item_no=1&attribute_id=65&file_no=1"}}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Unipolar depression","subitem_subject_scheme":"Other"},{"subitem_subject":"Bipolar disorder","subitem_subject_scheme":"Other"},{"subitem_subject":"Dexterity","subitem_subject_scheme":"Other"},{"subitem_subject":"Lithium","subitem_subject_scheme":"Other"},{"subitem_subject":"Antipsychotics","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"More severe impairment of manual dexterity in bipolar disorder compared to unipolar major depression","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"More severe impairment of manual dexterity in bipolar disorder compared to unipolar major depression"}]},"item_type_id":"20002","owner":"3","path":["2668"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-09-01"},"publish_date":"2020-09-01","publish_status":"0","recid":"27041","relation_version_is_last":true,"title":["More severe impairment of manual dexterity in bipolar disorder compared to unipolar major depression"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T22:11:39.100856+00:00"}