@article{oai:shinshu.repo.nii.ac.jp:00002190,
 author = {宮沢, 裕夫 and 金児, 晴夫 and 大島, 信一 and 吉田, 敦子 and 今西, 孝博 and 林, 春二 and 鈴木, 稔 and 半戸, 茂友},
 issue = {3},
 journal = {松本歯学},
 month = {Dec},
 note = {The oral cavity, on open-type organ contact with antibodies from the outside world through mucous membrane, has been reported to work as a neutralisirender antibody and Agglutination Antibody, and also as a defensive element against the invasion, settling and proliferation of pathogenic bacteria or other foreign bodies. It is, however, not yet clear as to what kind of role is played by Ig contained in the colostrum in the settling oral flora or caries activity whth regard to newborn or an infant. As a preliminary study to determine the role the amount of IgA in breast milk is playing in babies caries activity and the settling of oral flora, we examined the relationship of colostrum Ig with the amount of Ig contained in a babies saliva and the pH of that saliva. As result, the following findings have been made: 1. Although no what values in amount of saliva Ig were observed 24 hours after birth, an increasing tendency was noticed over the passage of time. 2. Although no correlation between IgA content of colostrum, IgA content of saliva and falling was observed either one month or three months after birth, the correlation coefficient was found to have become negative with the passage of time. 3. Although the difference in the Ig content of saliva caused by variation in the breast-milk ratio was not clearly noticeable, a tendency for the low breast-milk ratio group to show a higher Ig content of saliva was observed. 4. The group with the lower breast-milk ratio was found to have a pH value distributed over a low range of values. This tendency was particularly distinct three months after birth. 5. Whereas no change in pH was obseved with the passage of time in the case of the group with a breast-milk ratio of 100%, a distinct tendency of falling pH was ovserved in the case of the group fed entirely with artificial milk (i.e., 0% breast milk)., application/pdf},
 pages = {294--302},
 title = {口腔領域の局所免疫に関する研究 : 母乳Igの児への影響},
 volume = {17},
 year = {1991}
}