@article{oai:shinshu.repo.nii.ac.jp:00002101,
 author = {岩本, 雅章 and 野村, 寿 and 上條, 博之 and 大浦, 享子 and 太田, 紀雄 and 中村, 武 and 星野, 照宗},
 issue = {3},
 journal = {松本歯学},
 month = {Dec},
 note = {Periocline^[○!R] has been widely used for several years to treat periodontitis by means of the Local Drug Delivery System (LDDS), because of its high susceptibility to the bacteria causing periodontitis. Systemic administration of antibiotics (Tetracycline) for GJP creates a problem. However, our initial preparation of advanced GJP did not clinical improvement. Thus, we have taked pus discharged from the periodontal pocket of a patient with gingival abscess, separated main bacteria (P. intermedia, A. actinomycetemcomitans and Capnocytophaga sp.), and investigated the effect of Periocline^[○!R] on these main bacteria by applying it to the patient clinically. A case of a 24 year-old, male: first visit May 22, 1992-chief complaint, tooth mobility. The patient had gingival abscess with periodontal pocket (6～8mm) 521 1 1246 1246 Growth inhibitory zones obtained by MIC test were 32-52mm in diameter. Periocline^[○!R] (50 mg/tooth) applied eight times weekly reduced the level of GI and pocket depth (2～4mm)., application/pdf},
 pages = {307--314},
 title = {Local Drug Delivery Systemを用いた高度広汎型若年性歯周炎の一例},
 volume = {19},
 year = {1993}
}