@article{oai:shinshu.repo.nii.ac.jp:00002091,
 author = {鈴木, 和夫},
 issue = {3},
 journal = {松本歯学},
 month = {Dec},
 note = {Several qualities of materials are being used in implants. The biomaterial of the implants are usually classified as either non-bioactive or bioactive. Several studies have compared the interface of bone and different biomaterials. However, differences between the types of bone bonding, osseointegration, and contact osteogenesis have not been clarified. Formerly, titanium blade-vent implants were used for endosteal implants for a long time. Recently, various other forms and materials have been introduced for this purposes. The histological findings of these interface are also discussed in this introduction. The first cellular reaction occurs on the implant surface 1 to 3 weeks after implantation. Mononuclear phagocytes occur on the bone surface of the surrounding implant in this period. Preosteoblast and osteoblast are situated a distance of 30-50μm away from the implant surface. After 3 months, osteoblasts have reached the implant surface and bone formation is seen. The concept of osseointegration was originally introduced by Bränemark to describe the type of fibrous connective tissue-free anchorage of endosteal implant. Osseointegration is represented as healed bone in direct contact with a loaded implant surface. In the early period, movements of the implant encourage the formation of fibrous connective tissue at the implant interface. The loaded Ti-Ni Shape Memory alloy implant has been shown to come in direct contact with the bone, similar to osseointegration conditions. The hydroxyapatite coated implants (Sumicikon^[○!R]) designed by M.Ito and K. Suzuki in 1981, overcame the inter facial difficulty. The absence of fibrous encapsulation reaction allowing bonding between hydroxyapatite coating layer and the newly formed bone is an interesting phenomenon. The hydroxyapatite coated layer and the healing bone appeared to bind chemically at the interface., application/pdf},
 pages = {223--234},
 title = {歯科インプラント体と周囲骨組織の界面についての組織学的考察},
 volume = {19},
 year = {1993}
}