{"created":"2023-05-15T15:49:44.278297+00:00","id":1684,"links":{},"metadata":{"_buckets":{"deposit":"b803fdd2-06ce-4116-a39f-2111dc20ebfe"},"_deposit":{"created_by":3,"id":"1684","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"1684"},"status":"published"},"_oai":{"id":"oai:shinshu.repo.nii.ac.jp:00001684","sets":[]},"author_link":["4587","4579","4581","4586","4580","4583","4578","4584","4585","4582"],"item_20002_alternative_title_1":{"attribute_name":"その他(別言語等)のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"The Effects of Heat Treatment of Spherical Hydroxyapatite Particles on Osteoconductivity in Bone Defects"}]},"item_20002_biblio_info_27":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-12-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"237","bibliographicPageStart":"228","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"松本歯学"}]}]},"item_20002_creator_2":{"attribute_name":"作成者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"渡邉, 敏之"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"二宮, 禎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"細矢, 明宏"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"森山, 敬太"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"佐原, 紀行"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小澤, 英浩"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"溝口, 利英"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"佐伯, 達哉"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"伊藤, 充雄"}],"nameIdentifiers":[{}]}]},"item_20002_date_19":{"attribute_name":"日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-05-24","subitem_date_issued_type":"Created"}]},"item_20002_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Hydroxyapatite (HAP) shows different characteristics depending on the sintering temperature. However, the effects of the heat treatments on bone formation ability in bone defects have not been well elucidated. To develop bone filling materials having higher tissue affinity and superior bone conductivity, we attempt in this study to clarify the histological processes of osteosynthesis and osteogenesis in response to various heat-treated spherical HAP particles filled in bone defects. Spherical-shaped HAP particles (ca/p of more than 1.7) were heat-treated at 800℃ and 900℃ for 60 and 1440 minutes. Each HAP particle was examined in bone defects (diameter 3mm) surgically created in the calvaria of male rats. Demineralized sections were made and observed by light microscopy. Some non-demineralized specimens were examined by scanning electron microscopy. At 7 days after implantation, new bone formation occurred from the surface of bone defected cavity in all experimental groups. At 14 days, newly formed bone was observed only around the HAP particles heat-treated at 800℃ for 1440 minutes (the 800/1440 group). Bone formation of the 800/1440 groups was more rapid than in the other experimental groups. Furthermore, in the 800/1440 group, the number of TRAP positive multinucleated cells (osteoclast-like cells) resorbing HAP particles was much greater than that in other experimental groups throughout the experimental period. These results demonstrate that 800/1440 HAP particles have superior osteoconductivity and bioresorbability and suggest they may be useful as a filling material for bone defects.","subitem_description_type":"Other"}]},"item_20002_description_21":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_20002_full_name_16":{"attribute_name":"公開者(その他言語)","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"松本歯科大学学会"}]}]},"item_20002_identifier_23":{"attribute_name":"資源識別子URI","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"http://id.nii.ac.jp/1070/00000538/"}]},"item_20002_source_id_25":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-1613","subitem_source_identifier_type":"ISSN"}]},"item_20002_source_id_26":{"attribute_name":"処理レコードID(総合目録DB)","attribute_value_mlt":[{"subitem_source_identifier":"AN00232590","subitem_source_identifier_type":"NCID"}]},"item_20002_version_type_51":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"url":{"url":"https://mdu.repo.nii.ac.jp/?action=repository_action_common_download&item_id=538&item_no=1&attribute_id=22&file_no=1"}}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"骨補塡材","subitem_subject_scheme":"Other"},{"subitem_subject":"焼成","subitem_subject_scheme":"Other"},{"subitem_subject":"骨伝導","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"加熱処理が球状ハイドロキシアパタイトの骨欠損部での骨伝導能に与える影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"加熱処理が球状ハイドロキシアパタイトの骨欠損部での骨伝導能に与える影響"}]},"item_type_id":"20002","owner":"3","path":["2368"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-11-10"},"publish_date":"2022-11-10","publish_status":"0","recid":"1684","relation_version_is_last":true,"title":["加熱処理が球状ハイドロキシアパタイトの骨欠損部での骨伝導能に与える影響"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-05-15T19:43:13.476092+00:00"}