@article{oai:shinshu.repo.nii.ac.jp:00001517,
 author = {河住, 信 and 金子, 至 and 長谷川, 博雅 and 中村, 千仁 and 川上, 敏行 and 枝, 重夫},
 issue = {2},
 journal = {松本歯学},
 month = {Dec},
 note = {A multicentric tumor was spontaneously occurred in a 10-week-old female Wistar rat. It consisted of six, soft and dark-reddish-colored tubercles which ranged from soybean- to hen egg-size. They were so located near the mammillas that the tumor was suspected, of mammary gland origin. The animal was killed and the tubercles were examined by light and electron-microscopy. The tumor consisted of atypically proliferated cells forming a gland-like pattern which contained secreted materials. In some gland-like structures the tumor cells projected in papillary fashion into the spaces. Histochemistry on the materials revealed that these secreted materials contained both lipids and proteins. Based upon the above mentioned facts, this tumor was diagnosed as carcinoma papillotubulare which originated from the mammary glands. Electron microscopically the tumor cells were composed of gland cells and myoepithelial-cells. The former cells were rich in rough surfaced endoplasmic reticulum and contained many secreting granules which could be divided into electron-sparse large ones and electron-dense small ones., application/pdf},
 pages = {190--195},
 title = {ラットにみられた自然発生乳線原発腫瘍の病理組織学的ならびに電子顕微鏡的検索},
 volume = {9},
 year = {1983}
}