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Expression of RECK in endothelial cells of glioma: comparison with CD34 and VEGF expressions
https://shinshu.repo.nii.ac.jp/records/31402
https://shinshu.repo.nii.ac.jp/records/314024f021bc1-66de-4907-9f8d-add35b5ffc7f
名前 / ファイル | ライセンス | アクション |
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https://soar-ir.repo.nii.ac.jp/?action=repository_action_common_download&item_id=8056&item_no=1&attribute_id=65&file_no=1
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Item type | Journal Article(1) | |||||
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公開日 | 2020-09-02 | |||||
タイトル | ||||||
タイトル | Expression of RECK in endothelial cells of glioma: comparison with CD34 and VEGF expressions | |||||
作成者(その他言語) |
Rahmah, Nunung Nur
× Rahmah, Nunung Nur× Sakai, Keiichi× Sano, Kenji× Hongo, Kazuhiro |
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公開者(その他言語) | ||||||
姓名 | SPRINGER | |||||
書誌情報 |
JOURNAL OF NEURO-ONCOLOGY 巻 107, 号 3, p. 559-564, 発行日 2012-05 |
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言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Glioma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Microvascular density | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | RECK | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CD34 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | VEGF | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Angiogenesis is thought to be involved in the progression of glioma grades, and reversion-inducing cysteine-rich protein with Kazal motifs (RECK) has been said to be involved in maturation of vessels. In this study, we aimed to determine whether high micro-vessel density (MVD) expressed by RECK in glioma tissue is correlated with grades of glioma. We also compared RECK expression with that of the formerly known vessel marker, CD34, and vascular endothelial growth factor (VEGF). RECK, CD34, and VEGF immuno-reactivities of 72 glioma tissues were studied. RECK was seen in microvessels of glioma tissues. CD34 showed a similar pattern to RECK, whereas VEGF showed positive staining in cytoplasm of tumor cells and endothelial cells. Average MVD with RECK was 107.6 microvessels (range 7-290). RECK was positively correlated with grades of glioma. RECK and CD34 also showed a strong correlation (P = 0.001). Higher frequency of VEGF staining was also correlated with higher grade of glioma. This is the first study describing expression of RECK in glioma, and its angiogenesis-related nature may provide a potential therapeutic target for glioma treatment in the future. | |||||
日付 | ||||||
日付 | 2015-09-25 | |||||
日付タイプ | Created | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
その他の資源識別子 | ||||||
内容記述タイプ | Other | |||||
内容記述 | JOURNAL OF NEURO-ONCOLOGY. 107(3):559-564 (2012) | |||||
資源識別子URI | ||||||
識別子 | http://hdl.handle.net/10091/16943 | |||||
識別子タイプ | HDL | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0167-594x | |||||
処理レコードID(総合目録DB) | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10633712 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=22183444 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | http://dx.doi.org/10.1007/s11060-011-0778-z | |||||
権利 | ||||||
権利情報 | The final publication is available at www.springerlink.com | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |