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High concentrations of omega-3 fatty acids are associated with the development of atrial fibrillation in the Japanese population
https://shinshu.repo.nii.ac.jp/records/31390
https://shinshu.repo.nii.ac.jp/records/313904026b2de-4005-466e-bdcb-fe64a8acf02d
名前 / ファイル | ライセンス | アクション |
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https://soar-ir.repo.nii.ac.jp/?action=repository_action_common_download&item_id=8044&item_no=1&attribute_id=65&file_no=1
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Item type | Journal Article(1) | |||||
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公開日 | 2020-09-02 | |||||
タイトル | ||||||
タイトル | High concentrations of omega-3 fatty acids are associated with the development of atrial fibrillation in the Japanese population | |||||
作成者(その他言語) |
Tomita, Takeshi
× Tomita, Takeshi× Hata, Takeki× Takeuchi, Takahiro× Oguchi, Yasutaka× Okada, Ayako× Aizawa, Kazunori× Koshikawa, Megumi× Otagiri, Kyuhachi× Motoki, Hirohiko× Kasai, Hiroki× Izawa, Atsushi× Koyama, Jun× Hongo, Minoru× Ikeda, Uichi |
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公開者(その他言語) | ||||||
姓名 | SPRINGER | |||||
書誌情報 |
HEART AND VESSELS 巻 28, 号 4, p. 497-504, 発行日 2013-06 |
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言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Atrial fibrillation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Fatty acids | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Omega-3 fatty acids | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Risk factors | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | The favorable effect of fish oils rich in n-3 polyunsaturated fatty acids (PUFAs) on the development of atrial fibrillation (AF) is controversial. The relationship between the serum concentrations of n-3 PUFAs and the incidence of AF is unclear; therefore, in the present study, we aimed to elucidate this relationship. We evaluated the serum concentrations of n-3 PUFAs in 110 patients with AF, 46 patients with ischemic heart disease (IHD) and no AF, and 36 healthy volunteers. Thirty-six patients had a history of IHD (IHD-AF group) and 74 did not (L-AF group). The eicosapentaenoic acid (EPA) levels in the L-AF group were higher than those in the IHD-AF and control groups (117 +/- A 64, 76 +/- A 30, and 68 +/- A 23 mu g/ml, respectively); the docosahexaenoic acid (DHA) levels showed the same pattern (170 +/- A 50, 127 +/- A 27, and 126 +/- A 35 mu g/ml, respectively). In both the L-AF and IHD-AF groups, the EPA levels in patients with persistent and permanent AF were higher than those in patients with paroxysmal AF (L-AF 131 +/- A 74 vs. 105 +/- A 51 mu g/ml; IHD-AF 82 +/- A 28 vs 70 +/- A 33 mu g/ml). Multivariate analysis showed that cases of AF were associated with higher levels of EPA but not DHA. In this Japanese population study, the EPA and DHA levels in patients with L-AF were higher than those in normal subjects. In particular, the EPA level was associated with the incidence of AF. These findings suggest that an excess of EPA might be a precipitating factor of AF. | |||||
日付 | ||||||
日付 | 2015-09-25 | |||||
日付タイプ | Created | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
その他の資源識別子 | ||||||
内容記述タイプ | Other | |||||
内容記述 | HEART AND VESSELS. 28(4):497-504 (2013) | |||||
資源識別子URI | ||||||
識別子 | http://hdl.handle.net/10091/17344 | |||||
識別子タイプ | HDL | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0910-8327 | |||||
処理レコードID(総合目録DB) | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10452161 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=22696184 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | http://dx.doi.org/10.1007/s00380-012-0264-3 | |||||
権利 | ||||||
権利情報 | The original publication is available at www.springerlink.com | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |