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Association of cognitive performance with interleukin-6 receptor Asp358Ala polymorphism in healthy adults
https://shinshu.repo.nii.ac.jp/records/27039
https://shinshu.repo.nii.ac.jp/records/2703903c9101f-d7a3-4338-a7dc-81601cd575b8
名前 / ファイル | ライセンス | アクション |
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https://soar-ir.repo.nii.ac.jp/?action=repository_action_common_download&item_id=3693&item_no=1&attribute_id=65&file_no=1
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Item type | Journal Article(1) | |||||
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公開日 | 2020-09-01 | |||||
タイトル | ||||||
タイトル | Association of cognitive performance with interleukin-6 receptor Asp358Ala polymorphism in healthy adults | |||||
作成者(その他言語) |
Sasayama, Daimei
× Sasayama, Daimei× Hori, Hiroaki× Teraishi, Toshiya× Hattori, Kotaro× Ota, Miho× Matsuo, Junko× Kawamoto, Yumiko× Kinoshita, Yukiko× Amano, Naoji× Kunugi, Hiroshi |
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公開者(その他言語) | ||||||
姓名 | SPRINGER, WIEN | |||||
書誌情報 |
JOURNAL OF NEURAL TRANSMISSION 巻 119, 号 3, p. 313-318, 発行日 2012-03 |
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言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cognitive function | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Interleukin-6 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Genetic polymorphism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Intelligence | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Wechsler adult intelligence scale-revised was performed in 576 healthy adults to examine whether a functional polymorphism (Asp358Ala) of the IL-6 receptor (IL-6R) gene is associated with cognitive performance. Verbal intelligence quotient in Asp homozygotes was significantly higher compared to Ala carriers (P = 0.005). Compared to Ala carriers, Asp homozygotes performed better in the verbal subtests requiring long-term memory stores. Elevated IL-6 and soluble IL-6R levels in Ala carriers may have negative impact on acquiring verbal cognitive ability requiring long-term memory. | |||||
日付 | ||||||
日付 | 2015-09-24 | |||||
日付タイプ | Created | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
その他の資源識別子 | ||||||
内容記述タイプ | Other | |||||
内容記述 | JOURNAL OF NEURAL TRANSMISSION. 119(3):313-318 (2012) | |||||
資源識別子URI | ||||||
識別子 | http://hdl.handle.net/10091/17722 | |||||
識別子タイプ | HDL | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0300-9564 | |||||
処理レコードID(総合目録DB) | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11077137 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=21879314 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | http://dx.doi.org/10.1007/s00702-011-0709-3 | |||||
権利 | ||||||
権利情報 | The original publication is available at www.springerlink.com | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |