| Item type |
Journal Article(1) |
| 公開日 |
2020-09-01 |
| タイトル |
|
|
タイトル |
Toxicoproteomic evaluation of carbon nanomaterials in vitro |
| 作成者(その他言語) |
Haniu, Hisao
Matsuda, Yoshikazu
Usui, Yuki
Aoki, Kaoru
Shimizu, Masayuki
Ogihara, Nobuhide
Hara, Kazuo
Okamoto, Masanori
Takanashi, Seiji
Ishigaki, Norio
Nakamura, Koichi
Kato, Hiroyuki
Saito, Naoto
|
| 公開者(その他言語) |
|
|
|
姓名 |
Elsevier, B.V. |
| 書誌情報 |
Journal of Proteomics
巻 18,
号 12,
p. 2703-2712,
発行日 2011-11-18
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Toxicoproteomics |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Chronic toxicity |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Carbon nanotubes |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Nanomaterials |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
in vitro |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
metadata only access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Carbon nanotubes (CNTs) have already been successfully implemented in various fields, and they are anticipated to have innovative applications in medical science. However, CNTs have asbestos-like properties, such as their nanoscale size and high aspect ratio (> 100). Moreover, CNTs may persist in the body for a long time. These properties are thought to cause malignant mesothelioma and lung cancer. However, based on conventional toxicity assessment systems, the carcinogenicity of asbestos and CNTs is unclear. The reason for late countermeasures against asbestos is that reliable, long-term safety assessments have not yet been developed by toxicologists. Therefore, a new type of long-term safety assessment, different from the existing methods, is needed for carbon nanomaterials. Recently, we applied a proteomic approach to the safety assessment of carbon nanomaterials. In this review, we discuss the basic concept of our approach, the results, the problems, and the possibility of a long-term safety assessment for carbon nanomaterials using the toxicoproteomic approach. |
| 日付 |
|
|
日付 |
2015-09-18 |
|
日付タイプ |
Created |
| 資源タイプ |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Article |
| その他の資源識別子 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Journal of Proteomics. 74(12):2703-2712 (2011) |
| 資源識別子URI |
|
|
識別子 |
http://hdl.handle.net/10091/13337 |
|
識別子タイプ |
HDL |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1874-3919 |
| 処理レコードID(総合目録DB) |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11685085 |
| PubMed番号 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=21406258 |
| DOI |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://dx.doi.org/10.1016/j.jprot.2011.03.004 |
| 権利 |
|
|
権利情報 |
Copyright © 2011 Elsevier B.V. |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
https://soar-ir.repo.nii.ac.jp/?action=repository_action_common_download&item_id=365&item_no=1&attribute_id=65&file_no=1
