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The Effects of DMSA and DMPS on Arsenate Excretion in Mice
https://shinshu.repo.nii.ac.jp/records/1810
https://shinshu.repo.nii.ac.jp/records/1810f2259462-4123-42f8-b7dd-ee6f4b956b7a
名前 / ファイル | ライセンス | アクション |
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https://mdu.repo.nii.ac.jp/?action=repository_action_common_download&item_id=664&item_no=1&attribute_id=22&file_no=1
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Item type | Journal Article(1) | |||||
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公開日 | 2022-11-10 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | The Effects of DMSA and DMPS on Arsenate Excretion in Mice | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | 有害金属拮抗薬DMSAおよびDMPSのヒ酸ナトリウムの排泄に対する作用 | |||||
作成者 |
MIYAZAZWA, TOSHIKO
× MIYAZAZWA, TOSHIKO× NAITO, MAKOTO× MAEHASHI, HIROSHI |
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公開者(その他言語) | ||||||
姓名 | 松本歯科大学学会 | |||||
書誌情報 |
松本歯学 巻 26, 号 2-3, p. 102-105, 発行日 2000-12-31 |
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言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | DMSA | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | DMPS | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Arsenate excretion | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mice | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Previous studies have shown that DMSA (meso-2, 3-dimercaptosuccinic acid, succimer) and DMPS (2, 3-dimercapto-1-propane sulfonic acid, Na salt, unithiol) are effective antidotes for pentavalent arsenate and trivalent arsenite because they reduce the mortality of mice poisoned with these arsenic compounds. Studies have also shown that in mice treated with arsenite, DMPS and DMSA promote excretion of arsenic into the bile and urine, respectively. This study was conducted to determine whether DMSA and DMPS promote arsenate excretion to the same extent as previously reported for arsenite. The results demon-strated that DMPS antagonized arsenate toxicity by improving excretion of arsenic, although to a lesser extent than in studies with arsenite, while DMSA showed a slight but statistically insignificant promotion of early arsenic excretion in the urine. | |||||
日付 | ||||||
日付 | 2012-05-24 | |||||
日付タイプ | Created | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
資源識別子URI | ||||||
識別子 | http://id.nii.ac.jp/1070/00000664/ | |||||
識別子タイプ | URI | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0385-1613 | |||||
処理レコードID(総合目録DB) | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00232590 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |