| Item type |
Journal Article(1) |
| 公開日 |
2021-04-01 |
| タイトル |
|
|
タイトル |
Mouse subcutaneous tissue reaction to calcium hydroxide-based. |
|
言語 |
en |
| 作成者(その他言語) |
Shoumura, M
Matsuda, S
Osuga, N
Nakano, K
Tsujigiwa, H
Kawakami, T
|
| 公開者(その他言語) |
|
|
|
姓名 |
The, Hard Tissue Biology Network Association(JHTBNet) |
| 書誌情報 |
Journal of Hard Tissue Biology
巻 23,
号 4,
p. 435-438,
発行日 2014-10
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Calcium hydroxide |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Tissue reaction |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
macrophage |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
multi nucleated giant cells |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
TRAP |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
metadata only access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Mouse subcutaneous tissue reaction to an embedded calcium hydroxide-based root canal filling material was analyzed histopathologically. After the material was placed within the mouse dorsal subcutaneous tissues, we performed examinations using histopathological, histochemical and immunohistochemical techniques. Two weeks after embedment, the proliferation of granulation tissue had already begun to surround the calcification.Most of the cells observed were macrophages. Likewise, multinucleated giant cells increased significantly. The multinucleated giant cells were observed as two types. In one, the centers of the giant cells were vacuoles, while in the others there were deeply stained calcifications with hematoxylin. Twelve weeks after embedment of the materials, further growth of multinucleated giants cells were sighted. Histochemically, von Kossa-stainpositive granules were observed within the macrophages and multinucleated giant cells as black fine granules. According to the TRAP stained specimens, the multinucleated giant cells especially reacted strongly at 4 weeks. However, the reaction became very weak at 12 weeks. CD68 immunohistochemical staining showed positive reactions in the cytoplasm of the proliferating macrophages and multinucleated giant cells. These results suggest that multinucleated giant cells are present in the surrounding tissues due to implantation of the calcium hydroxidebased root canal filling material, and that the presence of ACP in the cells is due to ingested calcium during active phagocytosis, which would disappear later on. |
| 日付 |
|
|
日付 |
2015-12-04 |
|
日付タイプ |
Created |
| フォーマット |
|
|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| 資源識別子URI |
|
|
識別子 |
http://id.nii.ac.jp/1070/00002435/ |
|
識別子タイプ |
URI |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1341-7649 |
| 処理レコードID(総合目録DB) |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11074332 |
| 情報源 |
|
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|
関連名称 |
雑誌掲載論文(電子版) |
| 情報源 |
|
|
|
関連名称 |
http://doi.org/10.2485/jhtb.23.435 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.2485/jhtb.23.435 |
| NII論文ID |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
NAID |
|
|
関連識別子 |
http://ci.nii.ac.jp/naid/130004700428 |
| 医中誌ID |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
ICHUSHI |
|
|
関連識別子 |
https://search.jamas.or.jp/link/ui/2015325366 |
| 権利 |
|
|
権利情報 |
Copyright © 2014 Shoumura M et al by The Hard Tissue Biology Network Association(JHTBNet) |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
https://mdu.repo.nii.ac.jp/?action=repository_action_common_download&item_id=2444&item_no=1&attribute_id=22&file_no=1
