| Item type |
Journal Article(1) |
| 公開日 |
2022-11-10 |
| タイトル |
|
|
タイトル |
ウマ臼歯セメント質中のプロトカドヘリン18様物質の同定 |
| その他(別言語等)のタイトル |
|
|
その他のタイトル |
Identification of Protocadherin 18-like Protein in Horse Molar Cementum |
| 作成者 |
深澤, 加與子
佐原, 紀行
森山, 敬太
久野, 知子
藤井, 慈貴
音琴, 淳一
太田, 紀雄
宇田川, 信之
矢ケ﨑, 裕
小澤, 英浩
|
| 公開者(その他言語) |
|
|
|
姓名 |
松本歯科大学学会 |
| 書誌情報 |
松本歯学
巻 31,
号 2,
p. 160-166,
発行日 2005-08-31
|
| 言語 |
|
|
言語 |
jpn |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
ウマセメント質 |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
プロトカドヘリン18 |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
EDTA可溶画分 |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
プロコラーゲンα1 |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
metadata only access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Cementum plays an important role in tooth regeneration; however, the organization system has not yet been clarified. We have studied odontoclastic resorption in human deciduous teeth, and found that the cementum completely covers the enamel tissues of horse molar teeth. In order to study the regeneration system ofcementum, an EDTA soluble fraction extracted from horse cementum was analyzed. The 30 kDa protein was isolated from the EDTA fraction of horse cementum by hydroxyapatite chromatography and SDS-PAGE. Tryptic peptides obtained by Edman degradation of the 30 kDa protein were QDTGPRGPRGPAGP(1), GXRGFSLDGVK(2) and GYEFVITEHXLA(3). A search of the UniProt protein sequence database with peptide 1 and peptide 2 showed significant similarity to the two regions of Procollagen α 1 chain, residues 115-128(93%) and 266-277 (82%), respectively. The peptide 3 showed the highest similarity (85%) to the heptapeptide region of mouse Protocadherin 18. The 30 kDa protein would be a product from Type I collagen, a different splicing product translated from a 1 procollagen gene or a novel protein. Protocadherin 18 has not been identified in the oral tissues. This is the first report to find a protocadherin 18-like protein in cementum. Protocadherins are Ca<2+>-dependent adhesion molecules, and are highly expressed in the central nervous system. It is well known that protocadherins are involved in many biological processes such as tissue morphogenesis or cell differentiation events. Therefore, the protocadherin 18-like protein found in cementum might be expected to be involved in the regenerating system of cementum. |
| 日付 |
|
|
日付 |
2012-05-24 |
|
日付タイプ |
Created |
| フォーマット |
|
|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| 資源識別子URI |
|
|
識別子 |
http://id.nii.ac.jp/1070/00000519/ |
|
識別子タイプ |
URI |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0385-1613 |
| 処理レコードID(総合目録DB) |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN00232590 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
https://mdu.repo.nii.ac.jp/?action=repository_action_common_download&item_id=519&item_no=1&attribute_id=22&file_no=1
